Ari Zimran Selected Research

Tay-Sachs Disease

4/2015	Effect of cyclic, low dose pyrimethamine treatment in patients with Late Onset Tay Sachs: an open label, extended pilot study.
1/2012	Prevention of lysosomal storage diseases and derivation of mutant stem cell lines by preimplantation genetic diagnosis.

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Ari Zimran Research Topics

Disease

144	Gaucher Disease (Gaucher's Disease) 04/2024 - 01/2002
10	Parkinson Disease (Parkinson's Disease) 02/2024 - 02/2005
10	Thrombocytopenia (Thrombopenia) 12/2020 - 01/2002
7	Pain (Aches) 05/2023 - 01/2002
7	Anemia 12/2020 - 01/2002
6	Splenomegaly 12/2020 - 08/2012
5	Osteonecrosis (Kienbock's Disease) 05/2023 - 08/2003
5	Hemorrhage 11/2022 - 02/2004
5	Necrosis 10/2016 - 08/2003
4	Hepatomegaly 03/2018 - 05/2010
4	Osteoporosis 10/2016 - 01/2004
4	Tremor (Tremors) 09/2014 - 05/2003
4	Inflammation (Inflammations) 03/2010 - 01/2005
4	Pulmonary Hypertension 06/2007 - 08/2003
3	Body Weight (Weight, Body) 08/2023 - 02/2013
3	Hypersplenism (Anemia, Splenic) 04/2018 - 01/2002
3	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2018 - 11/2005
3	Hypersensitivity (Allergy) 02/2013 - 01/2009
3	Spontaneous Abortion (Miscarriage) 05/2011 - 02/2004
3	Bone Diseases (Bone Disease) 01/2011 - 08/2007
2	Disease Progression 01/2023 - 04/2016
2	Fatigue 10/2020 - 06/2012
2	Parkinsonian Disorders (Parkinsonism) 01/2020 - 06/2011
2	Metabolic Diseases (Metabolic Disease) 01/2018 - 12/2014
2	Clinical Deterioration 01/2016 - 07/2015
2	Tay-Sachs Disease 04/2015 - 01/2012
2	Cognitive Dysfunction 09/2014 - 02/2005
2	Chronic Disease (Chronic Diseases) 06/2012 - 02/2005
2	Neoplasms (Cancer) 01/2011 - 10/2009
2	Peripheral Nervous System Diseases (PNS Diseases) 10/2007 - 05/2003
2	Lung Diseases (Lung Disease) 06/2007 - 08/2003
2	Infections 02/2004 - 06/2002
1	Osteoarthritis 05/2023
1	Synucleinopathies 01/2022
1	Cough 01/2021
1	Postpartum Hemorrhage 01/2021
1	Hepatitis A (Hepatitis, Infectious) 12/2020
1	Respiratory Tract Diseases (Respiratory Tract Disease) 12/2020
1	Ganglion Cysts (Ganglion) 09/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2020
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2020
1	Neurologic Manifestations (Neurological Manifestations) 09/2019
1	Wandering Spleen 04/2018
1	Iron Overload 01/2018
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2018
1	Liver Diseases (Liver Disease) 01/2018
1	Dementia (Dementias) 04/2016
1	Aneuploidy (Aneuploid) 10/2015
1	Gastroenteritis 01/2015

Drug/Important Bio-Agent (IBA)

28	Glucosylceramidase (Glucocerebrosidase)IBA 01/2023 - 01/2003
22	imiglucerase FDA Link 03/2023 - 01/2007
18	EnzymesIBA 01/2022 - 07/2002
14	Biomarkers (Surrogate Marker)IBA 03/2023 - 05/2005
12	Glucosylceramides (Glucocerebrosides)IBA 02/2023 - 05/2003
11	taliglucerase alfaIBA 09/2023 - 11/2011
8	Ambroxol (Mucosolvan)IBA 04/2024 - 02/2013
8	sphingosyl beta-glucosideIBA 02/2023 - 01/2013
6	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2003
5	eliglustatIBA 10/2022 - 10/2014
5	AcidsIBA 01/2022 - 11/2005
5	chitotriosidaseIBA 01/2021 - 07/2005
5	Hemoglobins (Hemoglobin)IBA 03/2018 - 08/2002
5	LipidsIBA 01/2017 - 01/2002
5	miglustat (Zavesca)FDA Link 08/2013 - 03/2002
3	AntibodiesIBA 01/2016 - 01/2009
3	alglucerase FDA Link 09/2014 - 02/2009
3	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2011 - 01/2010
2	Anesthetics (Anesthetic Agents)IBA 08/2023 - 10/2005
2	SynucleinsIBA 01/2022 - 09/2014
2	GlycosphingolipidsIBA 12/2020 - 09/2020
2	Indicators and Reagents (Reagents)IBA 04/2016 - 08/2003
2	Immunoglobulin G (IgG)IBA 01/2016 - 11/2011
2	GlucosidasesIBA 12/2014 - 05/2011
2	Lysergic Acid Diethylamide (LSD)IBA 01/2013 - 01/2012
2	Prostaglandins DIBA 01/2012 - 01/2011
2	methyl 4-azidophenylacetimidate (APAI)IBA 01/2011 - 01/2010
2	C-Reactive ProteinIBA 05/2005 - 01/2005
2	pro-brain natriuretic peptide (1-76)IBA 05/2005 - 01/2004
2	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2005 - 01/2004
1	venglustatIBA 02/2024
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 11/2022
1	P-SelectinIBA 01/2022
1	IntegrinsIBA 01/2022
1	Expectorants (Mucolytics)IBA 01/2021
1	Retinaldehyde (Retinal)IBA 09/2020
1	Investigational DrugsIBA 01/2017
1	Levodopa (L Dopa)FDA LinkGeneric 04/2016
1	DNA (Deoxyribonucleic Acid)IBA 10/2015
1	Hexosaminidases (Hexosaminidase)IBA 04/2015
1	GD3 ganglioside (GD(3))IBA 09/2014

Therapy/Procedure

70	Enzyme Replacement Therapy 04/2024 - 01/2002
33	Therapeutics 04/2024 - 03/2002
11	Enzyme Therapy 08/2012 - 09/2002
9	Splenectomy 04/2018 - 01/2002
6	Arthroplasty 08/2023 - 12/2004
3	Hip Replacement Arthroplasty (Total Hip Replacement) 08/2023 - 03/2009
2	Drug Tapering 06/2011 - 05/2003
1	Minimally Invasive Surgical Procedures 04/2018
1	Intravenous Infusions 01/2018
1	Fluid Therapy (Oral Rehydration Therapy) 01/2015